Health / Medical Topics

    Donor Regulatory T-lymphocytes

    Donor-derived regulatory T-cells (Tregs), with potential immunomodulating activity. Tregs are a subset of CD4+ T cells that express high levels of CD25 (interleukin 2 receptor) and the transcription factor Foxp3. The donor CD4+CD25+ Tregs modulate immune responses and may induce tolerance to allogeneic organ transplants, such as hematopoietic stem cell transplants (HSCTs), thereby preventing graft-versus-host disease (GVHD). (NCI Thesaurus)




    YOU MAY ALSO LIKE

    A population of lymphocytes from the blood of a donor and administered to a patient who has already received a stem cell…
    A type of therapy in which lymphocytes from the blood of a donor are given to a patient who has already received…
    The subject contributing a heart for a cardiac transplant.
    A form of adoptive immunotherapy used after hematopoietic stem cell transplantation (HSCT). Lymphocytes from the original stem cell donor are given to…
    In medicine, a person who gives blood, cells, tissue, or an organ for use in another person, such as in a blood…
    A rare autosomal recessive genetic disorder caused by mutations in the insulin receptor gene. Signs and symptoms include a characteristic facial appearance…

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact