Health / Medical Topics

    DOT1L wt Allele

    Human DOT1L is located in the vicinity of 19p13.3 and is approximately 66 kb in length. This allele, which encodes histone lysine N-methyltransferase, H3 lysine-79 specific protein, may play a role in transcriptional regulation and epigenetic modification of chromatin. (NCI Thesaurus)




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