Drug interaction

Pronunciation

Definition 1

A change in the way a drug acts in the body when taken with certain other drugs, herbals, or foods, or when taken with certain medical conditions. Drug interactions may cause the drug to be more or less effective, or cause effects on the body that are not expected. (NCI Dictionary)

Definition 2

Alteration of the disposition and/or effect of a drug, owing to the presence of another factor such as a second drug, or food. (NCI Thesaurus)

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