Edotreotide

A chelated octreotide derivative with somatostatin activity. Edotreotide is produced by substituting tyrosine for phenylalanine at the 3 position of octreotide and chelated via dodecanetetraacetic acid (DOTA). Like octreotide, this edotreotide binds to somatostatin receptors (SSTRs), especially type 2, present on the cell membrane of many types of neuroendocrine tumors. When labeled with nuclides, edotreotide conjugates could result in tissue specific cytotoxicity. (NCI Thesaurus)

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Edotecarin

A substance being studied in the treatment of cancer. It is a type of topoisomerase I inhibitor. Also called J-107088.

EDNRB wt Allele

Human EDNRB wild-type allele is located in the vicinity of 13q22 and is approximately 24 kb in length. This allele, which encodes…

EDNRB Gene

This gene is involved in cell signaling.

EDNRA wt Allele

Human EDNRA wild-type allele is located in the vicinity of 4q31.23 and is approximately 64 kb in length. This allele, which encodes…

EDNRA Gene

This gene plays a role in signal transduction.

EDN2 wt Allele

Human EDN2 wild-type allele is located in the vicinity of 1p34 and is approximately 6 kb in length. This allele, which encodes…