Library / English Dictionary

EFFICACY

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

Capacity or power to produce a desired effect

Example:

concern about the safety and efficacy of the vaccine

Synonyms:

efficaciousness; efficacy

Classified under:

Nouns denoting attributes of people and objects

Hypernyms ("efficacy" is a kind of...):

effectiveness; effectivity; effectuality; effectualness (power to be effective; the quality of being able to bring about an effect)

Attribute:

efficacious (marked by qualities giving the power to produce an intended effect)

inefficacious (lacking the power to produce a desired effect)

Antonym:

inefficacy (a lack of efficacy)

Derivation:

efficacious (producing or capable of producing an intended result or having a striking effect)

efficacious (marked by qualities giving the power to produce an intended effect)

Credits

 Context examples: 

A standardized survey developed by W. Guy in 1976 which is used to evaluate the efficacy of a therapeutic intervention.

(Clinical Global Impression Questionnaire, NCI Thesaurus)

The type of clinical trial performed e.g. efficacy, safety.

(CDISC SDTM Trial Type Terminology, NCI Thesaurus/CDISC)

Upon PET imaging, tumor blood flow can be visualized and the efficacy of antineoplastic and anti-angiogenic chemotherapeutics can be assessed.

(Copper Cu 62 Ethylglyoxal Bis(thiosemicarbazone), NCI Thesaurus)

This results in increased anticancer efficacy while reducing side effects due to DACH-platin toxicity.

(DACH-Platin Micelle NC-4016, NCI Thesaurus)

By inducing the activity of the CYP3A4 enzyme, the metabolism of CYP3A4 substrates is increased, which leads to decreased bioavailability, plasma concentrations and reduced efficacy of these substrates.

(Cytochrome P450 3A4 Inducer, NCI Thesaurus)

Liposome encapsulation improves the efficacy and increases the half-life of OSI-7904.

(OSI-7904L, NCI Thesaurus)

By extending the circulation time and specifically targeting transferrin receptors, this formulation may improve the efficacy and safety of oxaliplatin therapy, compared to administration of oxaliplatin alone.

(Oxaliplatin-Encapsulated Transferrin-Conjugated N-glutaryl Phosphatidylethanolamine Liposome, NCI Thesaurus)

Select suitable vaccine candidates and support efficacy trials when appropriate criteria are met.

(Phase III Large Scale Vaccine Trial, NCI Thesaurus)

Combining a 16-week initial course of the medication omalizumab with oral immunotherapy (OIT) greatly improves the efficacy of OIT for children with allergies to multiple foods, new clinical trial findings show.

(Omalizumab improves efficacy of oral immunotherapy for multiple food allergies, National Institutes of Health)

The snarling of his dogs was losing its efficacy.

(White Fang, by Jack London)