Health / Medical Topics

    Eicosapentaenoic Acid

    Definition 1

    An essential, polyunsaturated, 20-carbon omega-3 fatty acid with anti-inflammatory and potential antineoplastic and chemopreventive activities. Eicosapentaenoic acid (EPA) may activate caspase 3, resulting in apoptosis in susceptible tumor cell populations. In addition, this agent may inhibit cyclooxygenase-2 (COX-2), resulting in inhibition of prostaglandin synthesis and prostaglandin-mediated inflammatory processes. (NCI Thesaurus)

    Definition 2

    A class of polyunsaturated fatty acids with 20 carbons and 5 double bonds. (NCI Thesaurus/CRCH)




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