EIF2AK3 wt Allele

Human EIF2AK3 wild-type allele is located in the vicinity of 2p12 and is approximately 71 kb in length. This allele, which encodes eukaryotic translation initiation factor 2-alpha kinase 3 protein, is involved in both protein phosphorylation and the negative regulation of translation. Mutation of the gene is associated with Wolcott-Rallison syndrome. (NCI Thesaurus)

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EIF2AK3 Gene

This gene plays a role in the regulation of translation.

EIF2AK2 wt Allele

Human EIF2AK2 wild-type allele is located within 2p22-p21 and is approximately 58 kb in length. This allele, which encodes interferon-induced, double-stranded RNA-activated…

EIF2AK2 Gene

This gene plays a role in the negative regulation of protein synthesis.

EIF2AK1 wt Allele

Human EIF2AK1 wild-type allele is located within 7p22 and is approximately 35 kb in length. This allele, which encodes eukaryotic translation initiation…

EIF2AK1 Gene

This gene plays a role in the negative regulation of protein synthesis.

eIF2 Regulation Pathway

Protein phosphorylation plays an important role in the control of translation by eukaryotic initiation factor-2 (eIF-2). eIF-2 binds GTP and Met-tRNAi and…