Health / Medical Topics

    EIF4A2 wt Allele

    Human EIF4A2 wild-type allele is located in the vicinity of 3q28 and is approximately 7 kb in length. This allele, which encodes eukaryotic initiation factor 4A-II, plays a role in the positive regulation of translation. A chromosomal translocation t(3;18)(q27;p11.2) of this gene and the BCL6 gene is associated with non-Hodgkin lymphoma. (NCI Thesaurus)




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