| Health / Medical Topics |
EL625
A phosphorothioate oligonucleotide harboring nucleotide sequences complementary to tumor suppressor p53 mRNA. EL625 hybridizes with p53 mRNA molecules, and induces Rnase H dependent hydrolysis of p53 transcripts in the double stranded section of the hybrids, thereby resulting in loss of p53 production. Loss of p53 activity leads to sensitization of cancer cells to other therapeutics. (NCI Thesaurus)
YOU MAY ALSO LIKE
A country in Central America, bordering the North Pacific Ocean, between Guatemala and Honduras.
The appearance of unusually warm waters in the eastern Pacific; termed the "Christ child" because of the time of year it effects…
A procedure used to do a mammogram (x-ray of the breasts) in women with breast implants. The implant is pushed back against…
A procedure used to do a mammogram (x-ray of the breasts) in women with breast implants. The implant is pushed back against…
A procedure used to do a mammogram (x-ray of the breasts) in women with breast implants. The implant is pushed back against…
A wild-type zebrafish line, the stock of which was obtained from Ekkwill Breeders (Florida).
