Health / Medical Topics

    Elongation Factor 1B1

    Encoded by human EEF1B1 Gene (EF1Beta/EF1Delta Family), 224-aa 24.6-kDa Elongation Factor 1B1 is a subunit of heterotrimeric Elongation Factor 1 (containing alpha/beta/gamma or alpha/delta/gamma subunits). Composed of an alpha subunit nucleotide binding domain and a beta/gamma subunit nucleotide exchange complex, Elongation Factor 1 is responsible for delivery of aminoacyl tRNAs to the ribosome. The homologous guanine nucleotide exchange factor EF-1-beta and EF-1-delta subunits stimulate GDP/GTP exchange bound to EF-1-alpha; phosphorylation affects the GDP/GTP exchange rate. (NCI Thesaurus)




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