Health / Medical Topics

    Elotuzumab

    Pronunciation

    Definition 1

    A humanized monoclonal antibody directed against the human CS1 (CD2 subset 1, CRACC, SLAMF7) antigen with potential antineoplastic activity. Elotuzumab binds to the CS1 antigen, which may trigger antibody-dependent cellular cytotoxicity (ADCC) in cells expressing CS1. CS1 is a cell surface glycoprotein belonging to the CD2 subset of the immunoglobulin superfamily (IgSF) and is highly expressed by multiple myeloma cells, but minimally expressed by normal cells. (NCI Thesaurus)

    Definition 2

    A monoclonal antibody being studied in the treatment of advanced multiple myeloma. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. HuLuc63 binds to CS1, a protein that is found mainly on the surface of multiple myeloma cells. (NCI Dictionary)




    YOU MAY ALSO LIKE

    Areas of the brain that control speech, motor functions, and sensory processing which are required for an individual to understand and interact…
    A protein complex that is involved in the elongation of RNA transcripts.
    Encoded by human EEF2 Gene (EF-G/EF-2 Family), highly conserved 857-aa 95-kDa cytoplasmic Elongation Factor 2 is essential for protein synthesis and required…
    Encoded by human EEF1B1 Gene (EF1Beta/EF1Delta Family), 224-aa 24.6-kDa Elongation Factor 1B1 is a subunit of heterotrimeric Elongation Factor 1 (containing alpha/beta/gamma…
    Elongation factor 1-gamma (437 aa, ~50 kDa) is encoded by the human EEF1G gene. This protein may play a role in the…
    Elongation factor 1-delta (281 aa, ~31 kDa) is encoded by the human EEF1D gene. This protein is involved in the positive regulation…

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact