| Health / Medical Topics |
EML4/ALK Fusion Gene Variant 3b
A fusion gene (~2.5 kb) that results from a chromosomal inversion inv(2)(p21p23) which fuses exon 6b of the EML4 gene with exons 20-29 of the ALK gene. This fusion is associated with non-small cell lung cancer. Multiple transcript variants are possible based on the breakpoint for the EML4 gene. (NCI Thesaurus)
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A fusion gene (~2.5 kb) that results from a chromosomal inversion inv(2)(p21p23) which fuses exon 6a of the EML4 gene with exons…
A fusion gene (~4.7 kb) that results from a chromosomal inversion inv(2)(p21p23) which fuses exon 20 of the EML4 gene with exons…
A fusion gene (~3.9 kb) that results from a chromosomal inversion inv(2)(p21p23) which fuses exon 13 of the EML4 gene with exons…
A fusion gene that results from a chromosomal inversion inv(2)(p21p23) which fuses the 5' portion of the EML4 gene with exons 20-29…
Human EML4 wild-type allele is located within 2p22-p21 and is approximately 163 kb in length. This allele which encodes echinoderm microtubule-associated protein…
This gene may play a role in cytoskeletal assembly.
