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Endothelin receptor antagonist
Pronunciation
Definition 1
A drug that blocks the hormone endothelin and may prevent prostate cancer from spreading to the bones. It may also prevent the growth and spread of other types of cancer, including colorectal cancer. (NCI Dictionary)
Definition 2
A group of agents that bind to endothelin receptors, thereby inhibiting the actions of endothelins. Inhibition of endothelins may decrease tumor growth, progression, and angiogenesis. (NCI Thesaurus)
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