Health / Medical Topics |
Eniluracil
Pronunciation
Definition 1
An anticancer drug that increases the effectiveness of fluorouracil. Also called ethynyluracil. (NCI Dictionary)
Definition 2
An orally-active fluoropyrimidine analogue. Eniluracil inhibits dihydropyrimidine dehydrogenase, the rate-limiting enzyme that catabolizes and inactivates 5-fluorouracil (5-FU) in the liver. Co-administration of ethynyluracil permits the oral administration of 5-FU. (NCI Thesaurus)
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