Health / Medical Topics

    Epithelial Atypical Hyperplasia of the Mouse Prostate Gland

    Definition 1

    Terms describing the degree of nuclear atypia, such as mild or severe, can be applied (analogous to distinctions between low and high grade PIN described below). However, the criteria, reproducibility, and biologic significance of such distinctions remain to be determined. (NCI Thesaurus/MMHCC)

    Definition 2

    Terms focal or diffuse can be applied to quantify the extent of atypical hyperplasia, with focal indicating one to several foci of epithelial hyperplasia within one to multiple gland lumens; diffuse, when greater than 50% of section involved. (NCI Thesaurus/MMHCC)




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