Health / Medical Topics

    epothilone D

    Pronunciation

    Definition 1

    A substance being studied in the treatment of cancer. It is a type of mitotic inhibitor and epothilone. Also called KOS-862. (NCI Dictionary)

    Definition 2

    A natural polyketide compound isolated from the myxobacterium Sorangium cellulosum. Also known as desoxyepothilone B, epothilone D binds to tubulin and inhibits the disassembly of microtubules, resulting in the inhibition of mitosis, cellular proliferation, and cell motility. (NCI Thesaurus)




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