| Health / Medical Topics |
epothilone ZK219477
Pronunciation
A form of the substance epothilone that is made in the laboratory. It is being studied in the treatment of some types of cancer. Epothilone ZK2219477 stops the growth of tumor cells by blocking cell division. It is a type of antimitotic agent. (NCI Dictionary)
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Analogues of epothilone B exhibiting antineoplastic activity. Epothilone B analogues bind to tubulin and promote tubulin polymerization and microtubule stabilization, thereby…
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An extract from the myxobacteria Sorangium cellulosum that promotes tubulin polymerization and microtubule stabilization, thereby inhibiting mitosis. Epothilone A appears to be…
