| Health / Medical Topics |
Eprosartan
A competitive and reversible angiotensin II receptor antagonist with anti-hypertensive property. Eprosartan blocks the binding of angiotensin II to the angiotensin (AT)1 receptor in vascular smooth muscle, thereby blocking the principal pressor action of angiotensin II on the renin-angiotensin system resulting in vascular dilatation. In addition, this agent blocks angiotensin II -induced stimulation of aldosterone synthesis and secretion by the adrenal cortex, cardiac contraction, renal resorption of sodium, activity of the sympathetic nervous system, and smooth muscle cell growth. Furthermore, eprosartan inhibits sympathetic norepinephrine production, thereby further reducing blood pressure. (NCI Thesaurus)
YOU MAY ALSO LIKE
The orally available disodium salt form of eprodisate, a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment…
A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called radiolabeled monoclonal…
The mission of the Eppley Cancer Center is to coordinate basic and clinical cancer research, patient care, and educational programs, and to…
Epoxide hydrolase 1 (455 aa, ~53 kDa) is encoded by the human EPHX1 gene. This protein is involved in the hydrolysis of…
A cyclic ether compound with a three-atom ring containing oxygen linked to two carbons. These rings are highly stressed and more reactive…
A form of the substance epothilone that is made in the laboratory. It is being studied in the treatment of some types…
