| Health / Medical Topics |
ErbB1
The protein found on the surface of some cells and to which epidermal growth factor binds, causing the cells to divide. It is found at abnormally high levels on the surface of many types of cancer cells, so these cells may divide excessively in the presence of epidermal growth factor. Also called EGFR, epidermal growth factor receptor, and HER1. (NCI Dictionary)
YOU MAY ALSO LIKE
An orally bioavailable inhibitor of the human epidermal growth factor receptor tyrosine kinase ErbB-2 (also called HER2) with potential antineoplastic activity. ErbB-2…
ERBB receptor feedback inhibitor 1 (462 aa, ~51 kDa) is encoded by the human ERRFI1 gene. This protein plays a role in…
A family of cellular proteins encoded by the c-erbB genes, including epidermal growth factor receptor. They are normally expressed in a variety…
The ErbB family of receptor tyrosine kinases (RTKs) couples binding of extracellular growth factor ligands to intracellular signaling pathways regulating diverse biologic…
A toxic substance linked to an antibody that attaches to tumor cells and kills them.
Retrovirus-associated DNA sequences originally isolated from, or related to, the avian erythroblastosis virus (AEV). The c-erbA proto-oncogene encodes the thyroid hormone receptors,…
