ERBB2 Gene Mutation

A molecular genetic abnormality indicating the presence of multiple copies of the ERBB2 gene.

This gene plays a role in cellular proliferation and is involved in the oncogenic process through amplification and/or overexpression in several…

The protein found on the surface of some cells and to which epidermal growth factor binds, causing the cells to divide. It…

An orally bioavailable inhibitor of the human epidermal growth factor receptor tyrosine kinase ErbB-2 (also called HER2) with potential antineoplastic activity. ErbB-2…

ERBB receptor feedback inhibitor 1 (462 aa, ~51 kDa) is encoded by the human ERRFI1 gene. This protein plays a role in…

A family of cellular proteins encoded by the c-erbB genes, including epidermal growth factor receptor. They are normally expressed in a variety…