ERBB3 wt Allele

Human ERBB3 wild-type allele is located within 12q13 and is approximately 23 kb in length. This allele, which encodes receptor tyrosine-protein kinase erbB-3 protein, is involved in the regulation of celullar proliferation and differentiation. Amplification or overexpression of this gene, has been documented in several solid tumors and cancers, including prostate, bladder, and breast. (NCI Thesaurus)

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ERBB3 Gene

This gene is involved in signal transduction pathways that result in cellular proliferation or differentiation. The gene has also been associated with…

ERBB2IP wt Allele

Human ERBB2IP wild-type allele is located in the vicinity of 5q12.3 and is approximately 156 kb in length. This allele, which encodes…

ERBB2IP Gene

This gene is involved in signal transduction and protein localization and function.

ERBB2 wt Allele

Human ERBB2 wild-type allele is located in the vicinity of 17q21.1 and is approximately 29 kb in length. This allele, which encodes…

ERBB2 Signaling Pathway

Her2 or ERBB2 belongs to a class of proteins having high homology with epidermal growth factor receptor (EGFR or ERBB1). It…