Ertapenem

A 1-beta-methyl carbapenem and broad-spectrum beta-lactam antibiotic with bactericidal property. Ertapenem binds to penicillin binding proteins (PBPs) located on the bacterial cell wall, in particular PBPs 2 and 3, thereby inhibiting the final transpeptidation step in the synthesis of peptidoglycan, an essential component of the bacterial cell wall. Inhibition results in a weakening and subsequent lysis of the cell wall leading to cell death of Gram-positive and Gram-negative aerobic and anaerobic pathogens. This agent is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, cephalosporinases and extended-spectrum beta-lactamases. (NCI Thesaurus)

YOU MAY ALSO LIKE

ERT

Treatment with the hormone estrogen to increase the amount of estrogen in the body. It is given to women who have gone…

Error Message Given Medical Device Problem

Issue associated with a device prompting user with an error message in order to indicate a device problem.

Error

A discrepancy between a computed, observed, or measured value or condition and the true, specified, or theoretically correct value or condition. …

ERRFI1 wt Allele

Human ERRFI1 wild-type allele is located in the vicinity of 1p36 and is approximately 22 kb in length. This allele, which encodes…

ERRFI1 Gene

This gene plays a role in the modulation of receptor signaling.

Erratics

Large boulders displaced from their natural geologic location by glaciers.