Library / English Dictionary

ESTRONE

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

A naturally occurring weak estrogenic hormone secreted by the mammalian ovary; synthesized (trade name Estronol) and used to treat estrogen deficiency

Synonyms:

estrone; Estronol; oestrone; theelin

Classified under:

Nouns denoting substances

Hypernyms ("estrone" is a kind of...):

estrogen; oestrogen (a general term for female steroid sex hormones that are secreted by the ovary and responsible for typical female sexual characteristics)

ketosteroid (a steroid containing a ketone group)

Credits

 Context examples: 

Estradiol, the principal intracellular human estrogen, is substantially more active at the cellular level than its metabolites, estrone and estriol.

(Estradiol, NCI Thesaurus)

Aromatase, a cytochrome P-450 enzyme localized to the endoplasmic reticulum of the cell and found in many tissues including those of the premenopausal ovary, liver, and breast, catalyzes the aromatization of androstenedione and testosterone into estrone and estradiol, the final step in estrogen biosynthesis.

(Letrozole, NCI Thesaurus)

As a third-generation aromatase inhibitor, anastrozole selectively binds to and reversibly inhibits aromatase, a cytochrome P-450 enzyme complex found in many tissues including those of the premenopausal ovary, liver, and breast; aromatase catalyzes the aromatization of androstenedione and testosterone into estrone and estradiol, the final step in estrogen biosynthesis.

(Anastrozole, NCI Thesaurus)