| Health / Medical Topics |
Etalocib
Definition 1
A second-generation selective leukotriene B4 receptor (LTB4R) antagonist with potential antineoplastic activity. Although the exact underlying mechanism through which LY293111 exerts its effects has not been fully elucidated, this agent selectively binds to and blocks LTB4Rs, thereby inhibiting the downstream signalling pathway. LY29311 has been shown to induce apoptosis and inhibits cellular proliferation in LTB4R expressing cells, such as pancreatic cancer cells. (NCI Thesaurus)
Definition 2
A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called leukotriene B4 receptor antagonists. (NCI Dictionary)
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