| Health / Medical Topics |
Etoposide phosphate
Pronunciation
Definition 1
A drug used to treat testicular and small cell lung cancers. It is also being studied in the treatment of several other types of cancer. Etoposide phosphate blocks certain enzymes needed for cell division and DNA repair, and it may kill cancer cells. It is a type of podophyllotoxin derivative and a type of topoisomerase inhibitor. Also called Etopophos. (NCI Dictionary)
Definition 2
A phosphate salt of a semisynthetic derivative of podophyllotoxin. Etoposide binds to the enzyme topoisomerase II, inducing double-strand DNA breaks, inhibiting DNA repair, and resulting in decreased DNA synthesis and tumor cell proliferation. Cells in the S and G2 phases of the cell cycle are most sensitive to this agent. (NCI Thesaurus)
YOU MAY ALSO LIKE
A drug used to treat testicular and small cell lung cancers. It is also being studied in the treatment of several other…
A drug used to treat testicular and small cell lung cancers. It is also being studied in the treatment of several other…
A synthetic form of the naturally occurring female sex hormone progesterone. Etonogestrel binds to the cytoplasmic progesterone receptors in the reproductive system…
An imidazole derivative with short-acting sedative, hypnotic, and general anesthetic properties. Etomidate appears to have gamma-aminobutyric acid (GABA) like effects, mediated through…
An epoxide compound with potential antineoplastic alkylating activity. Etoglucid is able to crosslink DNA via its epoxide group, resulting in disruption of…
The hydrochloride salt form of etoformin, a biguanide derivative with hypoglycemic activity.
