ETV6 wt Allele

Human ETV6 wild-type allele is located in the vicinity of 12p13 and is approximately 246 kb in length. This allele, which encodes transcription factor ETV6 protein, is involved in the repression of transcription by RNA polymerase II. Several malignancies, particularly leukemias, are linked to chromosomal translocations of this gene. (NCI Thesaurus)

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ETV6 Gene Mutation

A molecular genetic abnormality that refers to the presence of a mutation in the ETV6 gene (ETS variant gene 6).

ETV6 Gene

This gene plays a regulatory role in transcription and in matrix metalloproteinase activity.

ETV5 wt Allele

Human ETV5 wild-type allele is located in the vicinity of 3q28 and is approximately 64 kb in length. This allele, which encodes…

ETV5 Gene

This gene plays a role in the regulation of gene transcription.

ETV4 wt Allele

Human ETV4 wild-type allele is located in the vicinity of 17q21 and is approximately 18 kb in length. This allele, which encodes…

ETV4 Gene

This gene plays a regulatory role in transcription and in matrix metalloproteinase activity.