| Health / Medical Topics |
EWSR1/ATF1 Fusion Protein
A fusion protein encoded by the EWSR1/ATF1 fusion gene. This protein is comprised of the transactivation domain of the RNA-binding protein EWS followed by the DNA-binding basic domain and leucine zipper dimerization domain of the cyclic AMP-dependent transcription factor ATF-1 protein. (NCI Thesaurus)
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A fusion gene (~3.0 kb) that results from a chromosomal translocation t(12;22)(q13;q12) which fuses the first 7 exons of the EWSR1 gene…
A fusion gene (~3.3 kb) that results from a chromosomal translocation t(12;22)(q13;q12) which fuses the first 8 exons of the EWSR1 gene…
A fusion gene that results from a chromosomal translocation t(12;22)(q13;q12) which fuses the first 7 or 8 exons of the EWSR1 gene…
Human EWSR1 wild-type allele is located in the vicinity of 22q12.2 and is approximately 32 kb in length. This allele, which encodes…
This gene may play a role in post-transcriptional regulation; however the function remains to be elucidated. Mutations in the gene result in…
An antisense oligonucleotide that targets the type 8 form of EWS/FLI-1, an oncogenic fusion gene found in Ewing's sarcoma and primitive neuro-ectodermal…
