Health / Medical Topics |
F-Box/WD Repeat-Containing Protein 7
F-box/WD repeat-containing protein 7 (707 aa, ~80 kDa) is encoded by the human FBXW7 gene. This protein plays a role in the regulation of protein ubiquitination. (NCI Thesaurus)
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The F-box consists of three helices. The H1 helix packs orthogonally with the H2-H3 antiparallel pair. The F-box domain is a 42-48…