FAIRE-Seq

A molecular genetic technique that depletes a biological sample of nucleosomal DNA and then subjects the non-nucleosome-associated DNA to next-generation sequencing. Since nucleosome disruption of chromatin is indicative of active sites of DNA transcription, this technique can isolate DNA sequences that are involved in transcriptional regulation. First, a sample is treated with formaldehyde to form DNA-protein crosslinks, followed by sample lysis and sonication. The processed sample is subjected to phenol/chloroform extraction and the DNA in the aqueous phase is analyzed using next-generation sequencing techniques. (NCI Thesaurus)

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Having no exceptional quality or ability.

Fainting

Extremely weak; threatened with syncope.

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Issue associated with problems removing the materials used to construct the cover or outer wrapping of the device.

Failure to Thrive

A clinical finding indicating less than normal growth in an infant or child, or a state of global decline in an…

Failure to Spike Medical Device Problem

Failure of device to generate a correctly-shaped pacing output, for example, a waveform that is too wide.

Failure to Shock with Inadequate Defibrillator Threshold Safety Margin

The cardiac lead failed to administer a shock and had an inadequate defibrillator threshold safety margin.