| Library / English Dictionary |
FEEDBACK LOOP
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A circuit that feeds back some of the output to the input of a system
Synonyms:
feedback circuit; feedback loop
Classified under:
Nouns denoting man-made objects
Hypernyms ("feedback loop" is a kind of...):
circuit; electric circuit; electrical circuit (an electrical device that provides a path for electrical current to flow)
Hyponyms (each of the following is a kind of "feedback loop"):
control circuit; negative feedback circuit (a feedback circuit that subtracts from the input)
Context examples:
As the water again sinks, relatively warmer deep water replaces it, creating a feedback loop where ice can't form again.
(Data from robotic drifters explain mysterious holes in Antarctic sea ice, National Science Foundation)
The subsequent decrease in MPF levels, required to exit from MI into interkinesis, is induced by a negative feedback loop, where CDC2 brings about the activation of the APC (anaphase-promoting complex), which mediates destruction of cyclin B. Re-activation of MPF for MII requires re-accumulation of high levels of cyclin B as well as the inactivation of the APC by newly synthesized Emi2 and other components of the CSF (cytostatic factor), such as cyclin E or high levels of Mos.
(Oocyte Meiosis Pathway, NCI Thesaurus/KEGG)
Blocking the negative feedback loop would potentially increase PI3K signaling and decrease therapeutic efficacy.
(pan-PI3K/mTOR Inhibitor PQR309, NCI Thesaurus)
