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FEV wt Allele
Human FEV wild-type allele is located in the vicinity of 2q36 and is approximately 5 kb in length. This allele, which encodes protein FEV, may be involved in the negative regulation of transcription. Variation in the FEV gene may be associated with susceptibility to sudden infant death syndrome. A chromosomal translocation t(2;21;22)(q23;q22;q12) that fuses this gene and the EWSR1 gene is associated with Ewing sarcoma. (NCI Thesaurus)
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This gene may play a role in transcriptional repression.
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