Fexofenadine Hydrochloride

Definition 1

The hydrochloride salt form of fexofenadine, a carboxylated metabolic derivative of terfenadine and third generation selective histamine H1-receptor antagonist with antihistaminic and non-sedative effects. Fexofenadine competitively binds peripheral H1-receptors, thereby stabilizing an inactive conformation of the receptor. Consequently histamine binding and activity as a result of mast-cell degranulation followed by the release of multiple inflammatory mediators, such as interleukins, prostaglandin and leukotriene precursors, is blocked, thereby preventing the triggering of pro-inflammatory pathways. (NCI Thesaurus)

Definition 2

A drug used to treat certain allergy symptoms. It blocks a chemical released during an allergic response that causes itching, sneezing, runny nose, wheezing, and watery eyes. It is a type of antihistamine. (NCI Dictionary)

YOU MAY ALSO LIKE

Fexofenadine

A drug used to treat certain allergy symptoms. It blocks a chemical released during an allergic response that causes itching, sneezing, runny…

Few

An indefinite but relatively small number.

Fever of Unknown Origin

Fever in which the etiology cannot be ascertained.

Fever

An increase in body temperature above normal (98.6 degrees F), usually caused by disease.

FEV wt Allele

Human FEV wild-type allele is located in the vicinity of 2q36 and is approximately 5 kb in length. This allele, which encodes…

FEV Gene

This gene may play a role in transcriptional repression.