Health / Medical Topics

    FGF3 wt Allele

    Human FGF3 wild-type allele is located within 11q13 and is approximately 9 kb in length. This allele, which encodes INT-2 proto-oncogene protein, plays a role in cellular growth and signal transduction. Frequent amplification of this allele has been found in human tumors, which may be important for neoplastic transformation and tumor progression. (NCI Thesaurus)




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