| Health / Medical Topics |
FGFR1/ZMYM2 Fusion Gene
A fusion gene that results from a chromosomal translocation t(8;13)(p11;q12) which fuses the first 8 exons of the FGFR1 gene to exon 18 of the ZYZM2 gene. This rearrangement is associated with 8p11 myeloproliferative syndrome. (NCI Thesaurus)
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Human FGFR1 wild-type allele is located within 8p11.2-p11.1 and is approximately 56 kb in length. This allele, which encodes basic fibroblast growth…
FGFR1 oncogene partner 2 (253 aa, ~29 kDa) is encoded by the human FGFR1OP2 gene. This protein may be involved in wound…
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Rearrangement of the FGFR1 gene resulting in translocations with an 8p11 breakpoint. It has been described in hematologic malignancies presenting as myeloproliferative…
This gene plays a role in mitogenesis and differentiation.
