Health / Medical Topics |
FGFR1OP2/FGFR1 Fusion Gene
A fusion gene that results from a chromosomal insertion ins(12;8)(p11;p11p22) that fuses exon 4 of the FGFR1OP2 gene with exon 9 of the FGFR1 gene. This translocation is associated with 8p11 myeloproliferative disorder. (NCI Thesaurus)
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Human FGFR1OP2 wild-type allele is located in the vicinity of 12p11.23 and is approximately 28 kb in length. This allele, which encodes…
This gene may be involved in wound responses.
A fusion protein encoded by the FGFR1OP/FGFR1 fusion gene. This protein is comprised of the LIS1 homology domain of the FGFR1 oncogene…
A fusion gene that results from a chromosomal translocation t(6;8)(q27;p11) that fuses exon 5, 6 or 7 of the FGFR1OP gene with…
Human FGFR1OP wild-type allele is located within 6q27 and is approximately 41 kb in length. This allele, which encodes FGFR1 oncogene partner…
This gene is involved in the regulation of cell shape, polarity and motility.