| Health / Medical Topics |
FHIT wt Allele
Human FHIT wild-type allele is located in the vicinity of 3p14.2 and is approximately 1499 kb in length. This allele, which encodes bis(5'-adenosyl)-triphosphatase protein, is involved in the hydrolysis of P1-P3-bis(5'-adenosyl) triphosphate. FHIT gene dysfunction is associated with human cancers including carcinomas of the cervix, esophageus, lung, kidney, and stomach. (NCI Thesaurus)
YOU MAY ALSO LIKE
This gene is involved in nucleotide metabolism and cell cycle control.
Origin: An outbred stock of fawn hooded rats introduced into Europe by Tschopp in the early 1970s. Maintained as an outbred stock…
The FHA (Forkhead-Associated) domain is a phosphopeptide recognition domain found in many regulatory proteins. It displays specificity for phosphothreonine-containing epitopes but will…
It has been suggested that FH rats represent a genetic model of depression They have altered serotonergic function (Aulka et al, 1994a),…
Human FH wild-type allele is located in the vicinity of 1q42.1 and is approximately 22 kb in length. This allele, which encodes…
This gene plays a role in the Krebs cycle.
