Health / Medical Topics |
FJ5002
A derivative of rhodacyanine with potential antineoplastic activity. FJ5002 inhibits telomerase by interfering with holoenzyme assembly and telomere interaction, thus leading to replication-dependent shortening of telomeres with a concurrent increase in aneuploid metaphases and apoptotic cells. Telomerase is active in most tumors cells, but is quiescent in adjacent normal cells. (NCI Thesaurus)
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A real number with a fixed number of digits following the decimal or radix point.
Tissue which is preserved in a fixative solution, usually formalin.
A slide on which a fixed specimen has been mounted.
Round areas of red-purple reaction in the skin that result after drug exposure; these recur in the same location when the medication…
A compound that both fixes tissues or cells and stains it for microscopic study.
A compound that fixes tissues and cells for microscopic study.