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Folate antagonist
Pronunciation
Definition 1
A type of drug that stops cells from using folic acid to make DNA and may kill cancer cells. Certain folate antagonists are used to treat some types of cancer and inflammatory conditions, such as rheumatoid arthritis. Also called antifolate and folic acid antagonist. (NCI Dictionary)
Definition 2
A compound with a chemical structure similar to folic acid. Folate antagonists inhibit one or more folate-dependent enzymes, resulting in decreased DNA, RNA and protein synthesis. (NCI Thesaurus)
Definition 3
A substance that blocks the activity of folic acid. Folate antagonists are used to treat cancer. (NCI Dictionary)
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