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FOLFOX-6 regimen
Pronunciation
Definition 1
An abbreviation for a combination chemotherapy regimen that is used to treat colorectal cancer. It includes the drugs leucovorin calcium (folinic acid), fluorouracil, and oxaliplatin. There are several different FOLFOX regimens that differ in the doses and ways in which the three drugs are given. Also called FOLFOX-6. (NCI Dictionary)
Definition 2
A regimen consisting of leucovorin, infusional fluorouracil and oxaliplatin used for the treatment of advanced-stage and metastatic colorectal cancer. This particular version differs from the original FOLFOX (FOLFOX4) regimen with regards to both the doses and the administration of the three-drug combination. An alternative version, referred to as modified- FOLFOX6, is also used in clinical practice. (NCI Thesaurus)
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