Fomepizole

A pyrazole with competitive alcohol dehydrogenase inhibitor activity. Fomepizole prevents the metabolism of ethylene glycol and methanol by alcohol dehydrogenase, thereby inhibiting the formation of their toxic metabolites, glycolate and oxalate (from ethylene glycol), and formic acid (from methanol). Fomepizole is indicated for use as an antidote in ethylene glycol and methanol poisoning. (NCI Thesaurus)

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Folylpolyglutamate synthase, mitochondrial (587 aa, ~65 kDa) is encoded by the human FPGS gene. This protein plays a role in the conversion…

FOLR2 wt Allele

Human FOLR2 wild-type allele is located within 11q13.3-q14.1 and is approximately 5 kb in length. This allele, which encodes folate receptor beta…

FOLR2 Gene

This gene is involved in folic acid uptake.

FOLR1 wt Allele

Human FOLR1 wild-type allele is located within 11q13.3-q14.1 and is approximately 7 kb in length. This allele, which encodes folate receptor alpha…

FOLR1 Gene

This gene is involved in the mediation of 5-methyltetrahydrofolate delivery to the cellular interior.

FOLOTYN

A drug used in the treatment of peripheral T-cell lymphoma (a fast-growing form of non-Hodgkin lymphoma). It is also being studied in…