| Health / Medical Topics |
Fontolizumab
A humanized monoclonal antibody directed against interferon-gamma (IFN-g) with immunomodulatory activity. Fontolizumab binds to and prevents the activity of IFN-g. This leads to a suppression of IFN-g-mediated signaling and thus a suppression of IFN-g immune related responses. IFN-g is a cytokine often overexpressed in various auto-immune diseases. (NCI Thesaurus)
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