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Formation of Apurinic Site
Formation of Apurinic Site involves the creation of an apurinic site as a result of the loss of a purine residue from DNA. Purine residues are especially vulnerable to cleavage of the N-glycosylic bond between the purine residue and sugar moiety of the nucleotide, leaving in DNA a nucleotide position with no base attached. (NCI Thesaurus)
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