| Health / Medical Topics |
Fosphenytoin Sodium
The sodium salt form of fosphenytoin, a prodrug that is hydrolyzed to the anticonvulsant phenytoin upon parental administration. Phenytoin exerts its effect most likely through an enhancement of sodium efflux from neurons in the motor cortex. This leads to a suppression of excessive neuronal firing and spread of seizure activity. Other physiologic effects from actions of phenytoin include modulation of the voltage-dependent calcium channels of neurons, inhibition of calcium flux across neuronal membranes and enhancement of sodium-potassium ATPase activity of neurons and glial cells. (NCI Thesaurus)
YOU MAY ALSO LIKE
Human FOSL2 wild-type allele is located in the vicinity of 2p23.2 and is approximately 25 kb in length. This allele, which encodes…
This gene is involved in cellular proliferation and apoptosis.
Human FOSL1 wild-type allele is located in the vicinity of 11q13 and is approximately 8 kb in length. This allele, which encodes…
This gene plays a role in osteoclast differentiation and transcriptional activation.
A phosphinic acid-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Fosinoprilat specifically and competitively inhibits angiotensin-converting enzyme thereby decreasing the formation of…
The sodium salt of fosinopril, a phosphinic acid-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Fosinopril sodium is an ester prodrug that…
