Health / Medical Topics

    FOXD3 wt Allele

    Human FOXD3 wild-type allele is located within 1p32-p31 and is approximately 2 kb in length. This allele, which encodes forkhead box protein D3, plays a role in the regulation of transcription, neural tube differentiation and pluripotent stem cell maintenance during embryogenesis. Mutation of the gene is associated with autoimmune disease type 1. (NCI Thesaurus)




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