| Health / Medical Topics |
Frizzled 7
Frizzled 7, encoded by the human FZD7 gene, is a G protein-coupled receptor for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression downregulates APC function and enhances beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. (From LocusLink and NCI) (NCI Thesaurus)
YOU MAY ALSO LIKE
Frizzled 6, encoded by the human FZD6 gene, is a G protein-coupled receptor for Wnt signaling proteins. The FZD6 protein contains a…
Frizzled 4, encoded by the human FZD4 gene, is a G protein-coupled receptor that has seven transmembrane domains. This protein may play…
Frizzled 3 protein (666 aa, 76 kD) is a cell division process protein that is encoded by the human FZD3 gene and…
Frizzled 2, encoded by the human FZD2 gene, is a 7-transmembrane domain protein that is a receptor with a role in transmembrane…
Favorably disposed; not antagonistic or hostile.
A murine leukemia virus producing leukemia of the reticulum-cell type with massive infiltration of liver, spleen, and bone marrow. It infects DBA/2…
