| Health / Medical Topics |
FUS wt Allele
Human FUS wild-type allele is located in the vicinity of 16p11.2 and is approximately 12 kb in length. This allele, which encodes RNA-binding protein FUS, plays a role in the maintenance of genome integrity and the regulation of both RNA processing and gene expression. Mutation of the gene is associated with angiomatoid fibrous histiocytoma and amyotrophic lateral sclerosis. Translocations of the gene are associated with malignant myxoid liposarcoma, acute myeloid leukemia and angiomatoid fibrous histiocytoma. (NCI Thesaurus)
YOU MAY ALSO LIKE
This gene is involved in gene expression, genomic integrity and RNA processing.
A skin condition that is characterized by recurring furuncles, lesions primarily caused by staphylococcus aureus infection of the hair follicles and surrounding…
Bacterial infection of the hair follicle and the surrounding skin. It is caused by Staphylococcus aureus. It presents as a painful, erythematous…
To or at a greater distance in time or space.
A aminopteridine-based aldosterone antagonist with potassium-sparing diuretic activity. Furturene is able to antagonize aldosterone at the mineralocorticoid receptor in the kidneys, thereby…
A sulfamoylanthranilic acid derivative, also known as frusemide, and potent loop diuretic. Furosemide is widely used to treat hypertension and edema. This…
