Health / Medical Topics

    Galectin 8

    Constitutively and ubiquitously expressed by human LGALS8 Gene (S-Lectin Family), 316-amino acid 35.5-kD extracellular Galectin 8 contains two carbohydrate-binding (recognition) domains (CRDs) and binds to beta galactoside in cell adhesion, cell cycle regulation, inflammation, immunomodulation, apoptosis, and metastasis. Galectin 8 may be involved in activation of various cell types through cross-linkage of cell surface glycoproteins and may be involved in some types of cancer. (from LocusLink, Swiss-Prot, OMIM, and NCI) (NCI Thesaurus)




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