| Health / Medical Topics |
Ganciclovir
Pronunciation
Definition 1
An antiviral agent used to prevent or treat cytomegalovirus infections that may occur when the body's immune system is suppressed. In gene therapy, ganciclovir is used with an altered herpes simplex virus-1 gene to kill advanced melanoma cells and brain tumor cells. (NCI Dictionary)
Definition 2
A synthetic guanine derivative with antiviral activity. As the active metabolite of ganciclovir, ganciclovir-5-triphosphate (ganciclovir-TP) appears to inhibit viral DNA synthesis by competitive inhibition of viral DNA polymerases and incorporation into viral DNA, resulting in eventual termination of viral DNA elongation. (NCI Thesaurus)
YOU MAY ALSO LIKE
Human GAN wild-type allele is located in the vicinity of 16q24.1 and is approximately 65 kb in length. This allele, which encodes…
This gene plays a role in both neurofilament structure and ubiquitination.
A polyunsaturated long-chain fatty acid with an 18-carbon backbone and exactly three double bonds, originating from the 6th, 9th and 12th positions…
A genus of retroviridae comprising endogenous sequences in mammals, related reticuloendotheliosis viruses of birds, and a reptilian species. Many species contain oncogenes…
A resting, mature T cell that probably plays a primary role in suppressor/cytotoxic phenomena.
A complex comprised of gamma tubulin and other proteins that can act as a scaffold for the nucleation of microtubules.
