Ganglioglioma

Definition 1

A well differentiated, slow growing neuroepithelial neoplasm composed of neoplastic, mature ganglion cells and neoplastic glial cells. Some gangliogliomas show anaplastic features in their glial component and are considered to be WHO grade III. Rare cases of newly diagnosed gangliogliomas with grade IV (glioblastoma) changes in the glial component have also been reported. (NCI Thesaurus/Adapted from WHO)

Definition 2

A neuroepithelial neoplasm comprised of neoplastic ganglion cells and neoplastic glial cells, in which the malignancy status has not been established. (NCI Thesaurus/CDISC)

Definition 3

Rare indolent tumors comprised of neoplastic glial and neuronal cells which occur primarily in children and young adults. Benign lesions tend to be associated with long survival unless the tumor degenerates into a histologically malignant form. They tend to occur in the optic nerve and white matter of the brain and spinal cord. (NLM, Medical Subject Headings)

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