| Health / Medical Topics |
Ganglioneuroma
Definition 1
A benign neuroblastic tumor of the sympathetic nervous system that occurs in childhood. Ganglioneuroma typically arises from the sympathetic trunk in the mediastinum. Histologic features include spindle cell proliferation (resembling a neurofibroma) and the presence of large ganglion cells. Common presenting features include a palpable abdominal mass, hepatomegaly, and a thoracic mass detected on routine chest X-ray. (NCI Thesaurus)
Definition 2
A benign neoplasm characterized by the presence of ganglion cells and spindle cell proliferation, located primarily in the brain, ganglia, or adrenal medulla. (NCI Thesaurus/CDISC)
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